Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001548
Status:
COMPLETED
Last Update Posted:
2017-10-06
First Post:
1999-11-03
Brief Title:
Genetics of Obsessive-Compulsive Disorder
Sponsor:
National Institute of Mental Health NIMH
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Genetics of Obsessive-Compulsive Disorder A Collaborative Study
Status:
COMPLETED
Status Verified Date:
2015-09-29
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to identify genes that affect susceptibility to obsessive-compulsive disorder OCD By identifying genes that increase or decrease the risk of OCD researchers can better understand how the condition develops and ultimately improve treatment for people with OCD
OCD is a severe familial condition that affects approximately 2 of the population The way OCD is inherited is not clearly understood but researchers believe it is complex and involves multiple genes This study will detect and localize genes that increase or decrease susceptibility to OCD The data collected from this study will be combined with data from other research studies to determine gene linkage and association
OCD is a severe familial condition that affects approximately 2 of the population The way OCD is inherited is not clearly understood but researchers believe it is complex and involves multiple genes This study will detect and localize genes that increase or decrease susceptibility to OCD The data collected from this study will be combined with data from other research studies to determine gene linkage and association
Detailed Description:
Obsessive-compulsive disorder OCD is a severe heritable condition with a lifetime prevalence of about two percent of the population The mode of inheritance is poorly understood but is likely complex involving multiple loci of small to major effect Since 1995 the NIMH-IRP has been active in a multi-center family study of OCD led by Dr Gerald Nestadt of Johns Hopkins University which was approved via a competitive NIMH extramural application MH 502140 An expanded consortium of sites including new sites at Brown and Harvard Universities anticipates adding 300 new affected sib-pair families over the next three years This sample will be used for linkage and association analyses Data will be shared within this consortium of investigators studying OCD and will eventually be combined with data obtained from a second consortium
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 96-M-0124 | None | None | None |