Ignite Creation Date:
2024-05-05 @ 11:53 AM
Last Modification Date:
2024-10-26 @ 9:15 AM
Study NCT ID:
NCT00162396
Status:
UNKNOWN
Last Update Posted:
2008-10-29
First Post:
2005-09-11
Brief Title:
Genetic Determinants of the Response to Salbutamol Among Asthma Patients
Sponsor:
Hadassah Medical Organization
Organization:
Hadassah Medical Organization
Study Overview
Official Title:
Evaluation of Genetic Factors That May Account for Variability in the Response to Salbutamol Among Patients Suffering From Asthma
Status:
UNKNOWN
Status Verified Date:
2008-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The response to salbutamol varies greatly among individuals Data from previous studies indicate that some of the variability is accounted for by genetic polymorphisms in the gene encoding for the adrenoceptor subtype β2 The current study was designed to evaluate variability in the response to salbutamol among recently diagnosed patients who have not been treated by β2 agonists or corticosteroids
Lung function tests will be performed prior to and following a single dose administration of salbutamol through inhalation Additional pharmacodynamic indices will be monitored including pulse and blood pressure Three samples of plasma will be drawn for the evaluation of salbutamol plasma concentration
Lung function tests will be performed prior to and following a single dose administration of salbutamol through inhalation Additional pharmacodynamic indices will be monitored including pulse and blood pressure Three samples of plasma will be drawn for the evaluation of salbutamol plasma concentration
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None