Ignite Creation Date:
2024-05-05 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00151905
Status:
COMPLETED
Last Update Posted:
2007-05-07
First Post:
2005-09-07
Brief Title:
The Use of an Inhaled Salt Solution to Treat Viral Lung Infections in Infants
Sponsor:
Sheikh Khalifa Medical City
Organization:
Sheikh Khalifa Medical City
Study Overview
Official Title:
Nebulized Hypertonic Saline in the Treatment of Bronchiolitis in Infants
Status:
COMPLETED
Status Verified Date:
2005-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Bronchiolitis is a common viral lung infection in infants Standard treatment often includes the use of inhaled medications which are usually first mixed with a standard salt solution Inhalation of a more concentrated salt solution hypertonic saline has been successfully used to treat other types of lung disease in children and adults The purpose of this study is to see if using inhaled hypertonic saline helps infants with bronchiolitis get better more quickly
Detailed Description:
Bronchiolitis is a common illness in infants and is associated with a significant morbidity Standard therapy is controversial and largely ineffective care is mostly supportive although nebulized medications continue to be commonly used These medications are typically mixed with normal saline to produce a sufficient volume for efficient nebulization
Inhaled hypertonic saline has been used to aid airway clearance in children with cystic fibrosis It has also been used in low dose in two small studies in children with bronchiolitis The current study is a randomized double-blind placebo-controlled multi-center trial comparing frequent dosing with 3 hypertonic saline compared to normal saline in the treatment of infants hospitalized with bronchiolitis
Inhaled hypertonic saline has been used to aid airway clearance in children with cystic fibrosis It has also been used in low dose in two small studies in children with bronchiolitis The current study is a randomized double-blind placebo-controlled multi-center trial comparing frequent dosing with 3 hypertonic saline compared to normal saline in the treatment of infants hospitalized with bronchiolitis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None