Ignite Creation Date:
2024-05-05 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00151138
Status:
COMPLETED
Last Update Posted:
2007-12-17
First Post:
2005-09-06
Brief Title:
CognitiveCerebrovascular Consequences of HTN Treatment
Sponsor:
University of Pittsburgh
Organization:
University of Pittsburgh
Study Overview
Official Title:
Cognitive and Cerebrovascular Sequelae of Hypertension
Status:
COMPLETED
Status Verified Date:
2007-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Randomized trial of two antihypertensive drugs of known efficacy to investigate whether one has more favorable effects on brain blood flow and cognitive function
Detailed Description:
The project examines the neuropsychological status peripheral blood flow and structural cortical magnetic resonance imaging MRI and functional cortical blood flow quantitative positron emission tomography PET status of previously unmedicated hypertensives These individuals are then medicated for one year with one of two effective blood pressure medications Our hypothesis is that the angiotensin-converting enzyme inhibitor but not the beta-blocker will normalize cerebral blood flow and possibly cognitive function This hypothesis is tested by a repetition of our initial examinations at the completion of one year of treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL057529 | NIH | None | httpsreporternihgovquickSearchR01HL057529 |