Ignite Creation Date:
2024-05-06 @ 2:38 AM
Last Modification Date:
2024-10-26 @ 11:21 AM
Study NCT ID:
NCT02092428
Status:
COMPLETED
Last Update Posted:
2018-03-23
First Post:
2014-03-04
Brief Title:
Contrast- Enhanced Whole-Heart Coronary MRA at 30T Tesla
Sponsor:
Cedars-Sinai Medical Center
Organization:
Cedars-Sinai Medical Center
Study Overview
Official Title:
Contrast- Enhanced Whole-Heart Coronary Magnetic Resonance Angiography MRA at 30T
Status:
COMPLETED
Status Verified Date:
2018-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Investigators at the Biomedical Imaging Research Institute BIRI at Cedars-Sinai Medical Center have developed a Magnetic Resonance Imaging MRI method for imaging coronary arteries using slow-infusion contrast-enhanced data acquisition This method allows faster data acquisition and better spatial resolution
Specific aims of this study are to
1 compare coronary artery imaging with and without contrast media on both healthy subjects and patients
2 assess the accuracy of coronary MRI in detecting coronary artery disease as compared to conventional x-ray angiography
Researchers hypothesize that contrast-enhanced MRI will improve the delineation of coronary arteries over non-contrast-enhanced MRI and that optimized contrast-enhanced coronary MRI technique will accurately detect coronary artery disease CAD as compared to conventional x-ray angiography
Specific aims of this study are to
1 compare coronary artery imaging with and without contrast media on both healthy subjects and patients
2 assess the accuracy of coronary MRI in detecting coronary artery disease as compared to conventional x-ray angiography
Researchers hypothesize that contrast-enhanced MRI will improve the delineation of coronary arteries over non-contrast-enhanced MRI and that optimized contrast-enhanced coronary MRI technique will accurately detect coronary artery disease CAD as compared to conventional x-ray angiography
Detailed Description:
This is a study to compare image quality between contrast and non-contrast cardiac MR and to evaluate the diagnostic accuracy of a cardiac MRI procedure in a patient population that includes both healthy volunteers and a study group of patients with known CAD who are scheduled for clinical coronary angiography within one month of signing informed consent Both groups are eligible for a combination of imaging tests Subjects may receive either a non-contrast MRI or a contrast-enhanced MRI depending upon their kidney function and study focus Also based upon the focus of the study at the time of the scan and to improve image quality a beta-blocker to lessen motion artifact in patients with higher heart rates may be administered or patients may be asked to undergo a stress test for comparisonThis is a one-day research procedure Studies are acquired from the approved Institutional Review Board 25881 Cedars-Sinai Biomedical Imaging Research Registry
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 5R01EB002623-07 | NIH | None | httpsreporternihgovquickSearch5R01EB002623-07 |