Ignite Creation Date:
2024-05-06 @ 2:33 AM
Last Modification Date:
2024-10-26 @ 11:20 AM
Study NCT ID:
NCT02073396
Status:
COMPLETED
Last Update Posted:
2019-02-08
First Post:
2014-02-25
Brief Title:
Assessment of Thrombotic Status in Patients at Risk of Cardiovascular Thrombosis
Sponsor:
East and North Hertfordshire NHS Trust
Organization:
East and North Hertfordshire NHS Trust
Study Overview
Official Title:
Assessment of Thrombotic Status in Patients at Risk of Cardiovascular Thrombosis
Status:
COMPLETED
Status Verified Date:
2019-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with coronary artery disease CAD and atrial fibrillation AF are at increased risk of stroke and heart attack Such events are usually caused by increased stickiness of the blood causing a blood clot to block the artery thrombus in the heart or the brain The aim of this study is to assess the stickiness of the blood global thrombotic status in patients with CAD and AF at baseline and after clinical stabilisation to see how disease state and clinical treatments affect the stickiness of the blood thrombotic status This will be a single centre study Patients diagnosed with CAD or AF will have a blood sample taken at baseline and after clinical stabilisation Blood stickiness will be tested with the Global Thrombosis Test The results will be evaluated to assess the effect of disease process and clinical state on blood stickiness to gain further understanding of this condition and form the basis for future studies aimed at identifying patients who are at high risk of future cardiovascular events based on increased blood stickiness
Detailed Description:
Impaired thrombotic status is associated with adverse cardiovascular events Patients with coronary artery disease CAD and atrial fibrillation AF are at increased risk of thrombotic events It is not known whether thrombotic status differs in these patients or how thrombotic status alters in response to clinical stabilisation with treatment
The aim of this study is to assess the global thrombotic status stickiness of the blood in patients with coronary artery disease and atrial fibrillation at baseline and after clinical stabilisation
This is a small pilot hypothesis-generating study Design Single centre hypothesis-generating study Patients diagnosed with coronary disease n70 or atrial fibrillation n70 recruited from amongst in-patients or out-patients will have a blood draw at presentation and after clinical stabilisation Blood will be tested to assess global thrombotic status
The recruitment period is 3 years
The aim of this study is to assess the global thrombotic status stickiness of the blood in patients with coronary artery disease and atrial fibrillation at baseline and after clinical stabilisation
This is a small pilot hypothesis-generating study Design Single centre hypothesis-generating study Patients diagnosed with coronary disease n70 or atrial fibrillation n70 recruited from amongst in-patients or out-patients will have a blood draw at presentation and after clinical stabilisation Blood will be tested to assess global thrombotic status
The recruitment period is 3 years
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| REC 12EE0466 | OTHER | NRES Committee East of England - Essex UK | None |