Ignite Creation Date:
2024-05-06 @ 2:33 AM
Last Modification Date:
2024-10-26 @ 11:20 AM
Study NCT ID:
NCT02068560
Status:
COMPLETED
Last Update Posted:
2014-12-11
First Post:
2014-02-19
Brief Title:
The Effect of Gender on Antidiuresis - Evaluated by Graded Low Dose Desmopressin Infusion
Sponsor:
University of Aarhus
Organization:
University of Aarhus
Study Overview
Official Title:
The Effect of Gender on Antidiuresis - Evaluated by Graded Low Dose Desmopressin Infusion
Status:
COMPLETED
Status Verified Date:
2014-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
There is substantial evidence that women throughout life have significantly lower plasma levels of the antidiuretic hormone vasopressin pAVP compared to men The importance of this is not yet fully elucidated but in relation to the observations of lower pAVP levels no significant difference in renal response parameters was found This could be interpreted an increased renal sensitivity in females compared to males The theory of increased renal sensitivity in females is supported by a few pharmacodynamic studies currently available on this topic However none of the studies was designed with the purpose of investigate the gender difference
The aim of this study is to investigate possible gender differences in the renal sensitivity to dDAVP and the effect of age on these differences This will be done by low dose graded infusion of the synthetic AVP analog dDAVP
Participants are 80 healthy volunteers equally distributed between four age groups 8-10 years of age 16-18 years of age 25-40 years og age and 65 years of age
The aim of this study is to investigate possible gender differences in the renal sensitivity to dDAVP and the effect of age on these differences This will be done by low dose graded infusion of the synthetic AVP analog dDAVP
Participants are 80 healthy volunteers equally distributed between four age groups 8-10 years of age 16-18 years of age 25-40 years og age and 65 years of age
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None