Ignite Creation Date:
2024-05-06 @ 2:25 AM
Last Modification Date:
2024-10-26 @ 11:18 AM
Study NCT ID:
NCT02036710
Status:
COMPLETED
Last Update Posted:
2019-11-01
First Post:
2014-01-10
Brief Title:
Location of GLP-1 Release
Sponsor:
University of Minnesota
Organization:
University of Minnesota
Study Overview
Official Title:
Location of Glucagon-Like Peptide GLP-1 Release
Status:
COMPLETED
Status Verified Date:
2019-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Physicians do not have a unified scientifically tested theory of causation for obesity and its comorbidities nor do they have explanations for the mechanics of the metabolicbariatric surgery procedures Integral to proffered hypotheses are the actions of the hormones glucagon-like peptide GLP-1 peptide YY PYY and leptin
Study objective To obtain blood levels of GLP-1 PYY and leptin after stimulation of the terminal ileum and cecum by a static infusion of a food hydrolysate in morbidly obese patients undergoing a duodenal switch procedure
Methods Plasma levels of GLP-1 PYY and leptin were obtained at 0 30 60 90 and 120 minutes after instillation of 240 ml of a food hydrolysate into the ileum or cecum
Study objective To obtain blood levels of GLP-1 PYY and leptin after stimulation of the terminal ileum and cecum by a static infusion of a food hydrolysate in morbidly obese patients undergoing a duodenal switch procedure
Methods Plasma levels of GLP-1 PYY and leptin were obtained at 0 30 60 90 and 120 minutes after instillation of 240 ml of a food hydrolysate into the ileum or cecum
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None