Ignite Creation Date:
2024-05-06 @ 2:24 AM
Last Modification Date:
2024-10-26 @ 11:17 AM
Study NCT ID:
NCT02035176
Status:
COMPLETED
Last Update Posted:
2019-08-28
First Post:
2013-11-06
Brief Title:
Novel Measure of Social Deficits in Children
Sponsor:
Oregon Health and Science University
Organization:
Oregon Health and Science University
Study Overview
Official Title:
Oregon Animation Test for Social Reciprocity OATS
Status:
COMPLETED
Status Verified Date:
2019-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OATS
Brief Summary:
Autism Spectrum Disorders ASD feature impairments in social interaction and communication Drug and behavioral treatments for ASD are undergoing rapid development yet our diagnostic tools are not suitable for efficacy assessment The Autism-Diagnosis Observational Schedule ADOS is a clinical interview with the child and the gold standard for diagnosis However this test is subjective course grained and costly precluding repeated tests of the same child to assess treatment efficacy and large-scale control assessments of typically developing TD children For these reasons the ADOS can impede imaging and genetic research
In light of these concerns the Oregon Animation Test for Social Reciprocity OATS will be developed to evaluate distinct autistic behavioral phenotypes including joint attention empathy imitation and lack of narrative coherence The main idea of OATS is that animated characters and social scenarios are presented on a computer screen while the responses of the child are recorded by video camera microphone and eye-tracking equipment Animations are used to test each behavioral phenotype of autism The long-term vision for OATS is to evaluate behavioral and physiological responses of autistic children including heart rate variability pupil dilation and EEG Our first objective is to use existing animations to build an OATS Prototype that discriminates autistic from normal children Aim 1 From these results and use of a defined library of still frame posed images we will design our own animation platform to assess differences between autistic and normal children Aim 2
In light of these concerns the Oregon Animation Test for Social Reciprocity OATS will be developed to evaluate distinct autistic behavioral phenotypes including joint attention empathy imitation and lack of narrative coherence The main idea of OATS is that animated characters and social scenarios are presented on a computer screen while the responses of the child are recorded by video camera microphone and eye-tracking equipment Animations are used to test each behavioral phenotype of autism The long-term vision for OATS is to evaluate behavioral and physiological responses of autistic children including heart rate variability pupil dilation and EEG Our first objective is to use existing animations to build an OATS Prototype that discriminates autistic from normal children Aim 1 From these results and use of a defined library of still frame posed images we will design our own animation platform to assess differences between autistic and normal children Aim 2
Detailed Description:
Please see the brief summary above
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None