Ignite Creation Date:
2024-05-06 @ 2:20 AM
Last Modification Date:
2024-10-26 @ 11:17 AM
Study NCT ID:
NCT02022280
Status:
COMPLETED
Last Update Posted:
2022-08-23
First Post:
2013-12-03
Brief Title:
Effect of Proton Pump Inhibitors on Endothelial Function
Sponsor:
Stanford University
Organization:
Stanford University
Study Overview
Official Title:
Do Proton Pump Inhibitors PPIs Increase Cardiovascular Risk Effect of PPIs on Endothelial Function and ADMA
Status:
COMPLETED
Status Verified Date:
2022-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PPI
Brief Summary:
In this randomized controlled crossover study the investigators propose to test the hypothesis that proton pump inhibitors PPIs increase plasma levels of asymmetric dimethylarginine ADMA which is a marker of endothelial dysfunction The authors propose to evaluate ADMA concentrations and vascular function analysis in healthy volunteers and adults with a history of cardiovascular disease given PPI vs placebo for four weeks each
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1144447-121-DHAXB | OTHER_GRANT | Stanford Translational Research and Applied Medicine | None |