Viewing Study NCT01998516



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Study NCT ID: NCT01998516
Status: COMPLETED
Last Update Posted: 2017-09-20
First Post: 2013-11-12

Brief Title: Emotional Intelligence in Schizophrenia and Bipolar-I- Disorder
Sponsor: Medical University Innsbruck
Organization: Medical University Innsbruck

Study Overview

Official Title: Emotional Intelligence in Schizophrenia and Bipolar I Disorder a Comparison Between Patients Their Siblings and Healthy Controls
Status: COMPLETED
Status Verified Date: 2017-09
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Scientific Background

Emotional Intelligence EI as a part of social cognition is a rather new area of interest which focuses on personality traits and abilities enabling people to cope with both their own feelings as well as those of others The Mayer-Salovey-Caruso-Emotional-Intelligence-Test MSCEIT 1 represents a valid and reliable instrument which exclusively covers the emotional components of social cognition Recent findings indicate that social cognitive impairments are useful vulnerability indicators and that EI could be an endophenotype for schizophrenia and bipolar I disorder BD I To confirm the endophenotype theory studies concerning EI in relatives of schizophrenia and bipolar patients are needed To date studies on EI in BD patients as well as in first degree relatives of patients with schizophrenia or BD havent been conducted yet Accordingly the current study focuses on the four categories assessed by the MSCEIT and aims to compare the task performance of patients their first degree relatives and healthy control subjects We assume that the task performance of relatives lies between that of patients and controls The confirmation of this assumption would verify the trait marker hypothesis and could be a next step to identify a heritable endophenotype for schizophrenia and BD

Hypotheses

Compared to healthy control subjects patients suffering from schizophrenia or BD I show deficits in EI Siblings of patients with schizophrenia or BD I show deficits in EI and their task performance lies between that of patients and healthy controls Deficits in EI are more pronounced in schizophrenia patients than in patients with BD I and are more pronounced in siblings of schizophrenia patients than in siblings of patients with BD I Independently of diagnosis deficits in EI affect patients functional and subjective outcomes

Methods

Emotional Intelligence will be examined using the MSCEIT in patients with schizophrenia siblings of schizophrenia patients patients with BD I siblings of BD I patients and healthy volunteers matched for age sex and educational level Structured clinical interviews according to DSM-IV MINI SCID II will be carried out to assure the diagnosis of schizophrenia or bipolar disorder as well as to detect comorbid Axis I and Axis II psychiatric disorders patients siblings control subjects Functional outcome will be assessed by using the GAF Global Assessment of Functioning Scale and the PSP Personal and Social Performance Scale subjective quality of life will be examined using the BELP Berliner Lebensqualiätsprofil The MWT-B Multiple choice vocabulary test will be used to assess premorbid intelligence
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None