Ignite Creation Date:
2024-05-05 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00145756
Status:
COMPLETED
Last Update Posted:
2005-09-05
First Post:
2005-09-02
Brief Title:
China Salt Substitute Study
Sponsor:
The George Institute
Organization:
The George Institute
Study Overview
Official Title:
China Salt Substitute Study-A Randomised Trial to Determine the Long-Term Effects of a Low Sodium High Potassium Salt Substitute on Blood Pressure Among High-Risk Individuals in Northern China
Status:
COMPLETED
Status Verified Date:
2005-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Cardiovascular disease is a leading cause of death and disability worldwide and blood pressure is a leading determinant of this risk To date strategies for blood pressure lowering have focused on drug treatment but dietary interventions such as reducing sodium intake and increasing potassium intake may also be effective Such interventions may be particularly suitable for low- and middle-income countries in which significant dietary changes may be more easily achieved This study will test the effect of a salt substitute on blood pressure among individuals at high-risk from cardiovascular disease in Northern China
Detailed Description:
This randomised trial will clearly identify whether a low-sodium high-potassium salt-substitute is a feasible means of lowering blood pressure in high-risk individuals in rural China The randomised design and the large size n600 will ensure that the results are reliable and precise The 12-month duration will address the long-term practicability of the intervention strategy The study is being conducted because salt-substitute-based blood pressure lowering may be particularly appropriate for rural populations in low- and middle-income countries First sodium intake is often very high Second the salt-substitute can be easily incorporated into the diet because most food is prepared and eaten at home Third the intervention can be provided at very low cost
Comparisions Low sodium high potassium salt 65 sodium chloride 25 potassium chloride 10 magnesium sulphate compared to normal salt 100 sodium chloride
Comparisions Low sodium high potassium salt 65 sodium chloride 25 potassium chloride 10 magnesium sulphate compared to normal salt 100 sodium chloride
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None