Ignite Creation Date:
2024-05-05 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00145392
Status:
COMPLETED
Last Update Posted:
2008-06-24
First Post:
2005-09-02
Brief Title:
Body Composition Glucose Metabolism Insulin Resistance and Gene Expression in Muscle Cells in Healthy Overweight Women
Sponsor:
Odense University Hospital
Organization:
Odense University Hospital
Study Overview
Official Title:
Body Composition Glucose Metabolism Insulin Resistance and Gene Expression in Muscle Cells in Healthy Overweight Women
Status:
COMPLETED
Status Verified Date:
2008-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study we will clarify the degree of insulin resistance and characterise muscle glucose metabolism and gene expression in a group of overweight healthy women The study will clarify how overweight influences body glucose metabolism and thereby in the long-run increases the risk for developing type 2 diabetes Moreover the study may clarify why some overweight women develop hormone disorders and diabetes while others remain healthy
The study is essential as many patients suffer from diseases aggravated by overweight In addition a genetic disposition for diabetes or polycystic ovary syndrome may give rise to the disease if the patient gains weight It is therefore important that weight-matched control subjects are included in projects with overweight patients
This clinical trial includes 10 overweight women with regular hormones and normal level of male sex hormone The patients included must be healthy take no medications influencing the study results The subjects must take no contraceptive pills or receive any other hormone treatment
In connection with the investigation the following will be carried out on all patients clinical examination blood tests hyperinsulinaemic euglycaemic clamp muscle biopsies bone scan
The purpose of the study is to gain more knowledge of how overweight influences womens risk of developing hormone diseases and diabetes
The study is essential as many patients suffer from diseases aggravated by overweight In addition a genetic disposition for diabetes or polycystic ovary syndrome may give rise to the disease if the patient gains weight It is therefore important that weight-matched control subjects are included in projects with overweight patients
This clinical trial includes 10 overweight women with regular hormones and normal level of male sex hormone The patients included must be healthy take no medications influencing the study results The subjects must take no contraceptive pills or receive any other hormone treatment
In connection with the investigation the following will be carried out on all patients clinical examination blood tests hyperinsulinaemic euglycaemic clamp muscle biopsies bone scan
The purpose of the study is to gain more knowledge of how overweight influences womens risk of developing hormone diseases and diabetes
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None