Ignite Creation Date:
2024-05-05 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00145015
Status:
COMPLETED
Last Update Posted:
2008-07-30
First Post:
2005-09-01
Brief Title:
FishGastro Study Fish Consumption and Gastro-Intestinal Health
Sponsor:
Quadram Institute Bioscience
Organization:
Quadram Institute Bioscience
Study Overview
Official Title:
Fish Consumption and Gastro-Intestinal Health With Special Emphasis on Reduction of Risk of Colon Cancer and Inflammatory Bowel Disease
Status:
COMPLETED
Status Verified Date:
2008-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the study is to determine whether increasing the dietary intake of n-3 fatty acids by the consumption of oil-rich fish reduces the risk of developing colorectal cancer
Detailed Description:
Epidemiological evidence from several countries supports a protective effect of fish consumption on cancer risk and gastrointestinal cancers in particular Further evidence to support the idea that fish consumption is protective in relation to cancers of the GI tract is now emerging from the European Investigation into Cancer and Nutrition EPIC
The FISHGASTRO project is headed by the Institute of Food Research and includes groups from the University of East Anglia the University of Wageningen Netherlands and the University of Jena Germany The project focuses on assessing the impact of fish consumption on a range of markers of gastrointestinal health associated with ulcerative colitis or colon cancer and on looking at bio-accessibility of a range of nutrients from fish We aim to recruit a total of 270 patients with gastrointestinal problems in the UK and Netherlands and take biopsy and blood samples before and after asking them to eat two extra portions of fish per week One group will receive oil rich fish such as salmon while another will be asked to eat white fish Changes in cell proliferation apoptosis inflammatory markers gene expression and plasma levels of n-3 fatty acids will be compared to a control group only given standard nutritional advice
The FISHGASTRO project is headed by the Institute of Food Research and includes groups from the University of East Anglia the University of Wageningen Netherlands and the University of Jena Germany The project focuses on assessing the impact of fish consumption on a range of markers of gastrointestinal health associated with ulcerative colitis or colon cancer and on looking at bio-accessibility of a range of nutrients from fish We aim to recruit a total of 270 patients with gastrointestinal problems in the UK and Netherlands and take biopsy and blood samples before and after asking them to eat two extra portions of fish per week One group will receive oil rich fish such as salmon while another will be asked to eat white fish Changes in cell proliferation apoptosis inflammatory markers gene expression and plasma levels of n-3 fatty acids will be compared to a control group only given standard nutritional advice
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None