Ignite Creation Date:
2024-05-06 @ 1:56 AM
Last Modification Date:
2024-10-26 @ 11:12 AM
Study NCT ID:
NCT01936051
Status:
COMPLETED
Last Update Posted:
2019-04-08
First Post:
2013-08-27
Brief Title:
Modeling Between Plasma Concentration and Serotonin Transporter Occupancy Induced by Escitalopram in Obsessive-compulsive DisorderOCD Patients
Sponsor:
Seoul National University Hospital
Organization:
Seoul National University Hospital
Study Overview
Official Title:
Modeling Between Plasma Concentration and Serotonin Transporter Occupancy Induced by Escitalopram in Obsessive-compulsive DisorderOCD Patients
Status:
COMPLETED
Status Verified Date:
2019-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To modeling the pharmacokinetic-pharmacodynamicPK-PD simulation with the plasma concentration and the transporter occupancy from OCD patients treated with escitalopram
To examine the effect of G2677TA single nucleotide polymorphismSNP of ABCB1 gene to the PK-PD modeling in OCD patients treated with escitalopram
To examine the effect of G2677TA single nucleotide polymorphismSNP of ABCB1 gene to the PK-PD modeling in OCD patients treated with escitalopram
Detailed Description:
To measure plasma concentration of escitalopram in OCD patients treated with escitalopram
To measure serotonin transporter occupancy by escitalopram in OCD patients treated with escitalopram
To genotype G2677TA SNP of ABCB1 gene in OCD patients treated with escitalopram
To measure serotonin transporter occupancy by escitalopram in OCD patients treated with escitalopram
To genotype G2677TA SNP of ABCB1 gene in OCD patients treated with escitalopram
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2011-0931 | OTHER | Seoul National university Hospital IRB | None |