Ignite Creation Date:
2024-05-05 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00149253
Status:
COMPLETED
Last Update Posted:
2005-09-08
First Post:
2005-09-06
Brief Title:
Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain
Sponsor:
Khon Kaen University
Organization:
Khon Kaen University
Study Overview
Official Title:
A Randomized Double-Blind Controlled Trial of Etoricoxib as a Pre-Emptive Analgesic for Abdominal Hysterectomy
Status:
COMPLETED
Status Verified Date:
2004-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Taken together studies of the value of pre-emptive analgesia are inconclusive This randomized double-blind dose-ranging placebo-controlled study was therefore designed to test that a reduction in post-operative morphine consumption can be achieved by a single-dose of etoricoxib before induction of anesthesia
Detailed Description:
Patients undergoing transabdominal hysterectomy were randomized to a group taking a single dose orally of etoricoxib 120 mg n 18 etoricoxib 180 mg n 17 or placebo n 15 2 hours before surgery under the same standardized general anesthesia At the post-anesthetic care unit intravenous morphine titration was given before starting self-controlled analgesia PCA device Morphine consumption pain relief score sedative score global evaluation score and side-effects were recorded at 1 2 4 8 and 24 h post-operatively The primary end points were morphine consumption within 24-hr post-operatively and total pain relief over 8 h TOPAR8 Patient global satisfaction was also assessed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Faculty of MedicineKhonKaenU | None | None | None |