Ignite Creation Date:
2024-05-05 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 9:13 AM
Study NCT ID:
NCT00136383
Status:
COMPLETED
Last Update Posted:
2014-07-21
First Post:
2005-08-25
Brief Title:
Comparing Paroxetine and Duloxetine on Cardiovascular Measures
Sponsor:
Duke University
Organization:
Duke University
Study Overview
Official Title:
A Study of the Effects of Paroxetine vs Duloxetine on Heart Rate Variability and Autonomic Cardiovascular Control
Status:
COMPLETED
Status Verified Date:
2007-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This double-blind placebo-controlled trial is designed to test and to compare the cardiovascular profile of paroxetine controlled release CR with duloxetine in outpatients with depressive symptoms
Detailed Description:
This double-blind placebo-controlled study will test the hypothesis that greater reduction in heart rate variability will be associated with duloxetine than paroxetine in outpatients with major depressive disorder We will also examine the relationship between changes in heart rate variability to the magnitude of serotonin and norepinephrine transporter occupancy produced by each drug
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 6956-05-3R0 | OTHER | DUMC | None |