Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005423
Status:
COMPLETED
Last Update Posted:
2016-03-16
First Post:
2000-05-25
Brief Title:
Dietary Quality and Subsequent Cardiovascular Disease
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2002-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine dietary quality and subsequent cardiovascular disease CVD
Detailed Description:
BACKGROUND
Although considerable evidence exists for associations between diet and subsequent cardiovascular disease CVD among younger and middle-aged adults no comprehensive studies of these relationships have been conducted using a national sample of older Americans National guidelines have recommended reductions of dietary fat saturated fat cholesterol and sodium as dietary practice to reduce CVD However it is possible that the focus on eliminating dietary components may obscure the advantages of consuming diets that are nutritionally adequate
Findings from this study could have important implications for setting research priorities to further study the effects of specific dietary variables on CVD and for implementing national nutrition policies to assist Americans in selecting healthy diets
DESIGN NARRATIVE
Data from NHANES I and the three cycles of NHANES I Epidemiologic Followup Study NHEFS were used to 1 to examine the associations between several measures of dietary quality at baseline and subsequent 14-year morbidity and mortality from CVD for a national sample of 6109 United States adults aged 45 to 74 years at baseline 2 to assess the relative importance of the associations of dietary quality and CVD for older adults compared to middle-aged adults Dietary variables were based on responses to the 24-hour dietary recall and the food frequency questionnaire administered at baseline and included a composite measure of dietary quality intakes of specific nutrients and usual consumption of foods from 19 food groups Baseline measures used as covariates included body mass index blood pressure serum cholesterol sociodemographic variables eg age race income occupation behavioral variables eg smoking alcohol consumption activity level and chronic health conditions CVD outcomes were determined from medical history questionnaires hospital records and death certificates Change in blood pressure between baseline and 10-year followup were examined as an outcome variable as well as a covariate in the association between diet and CVD
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Although considerable evidence exists for associations between diet and subsequent cardiovascular disease CVD among younger and middle-aged adults no comprehensive studies of these relationships have been conducted using a national sample of older Americans National guidelines have recommended reductions of dietary fat saturated fat cholesterol and sodium as dietary practice to reduce CVD However it is possible that the focus on eliminating dietary components may obscure the advantages of consuming diets that are nutritionally adequate
Findings from this study could have important implications for setting research priorities to further study the effects of specific dietary variables on CVD and for implementing national nutrition policies to assist Americans in selecting healthy diets
DESIGN NARRATIVE
Data from NHANES I and the three cycles of NHANES I Epidemiologic Followup Study NHEFS were used to 1 to examine the associations between several measures of dietary quality at baseline and subsequent 14-year morbidity and mortality from CVD for a national sample of 6109 United States adults aged 45 to 74 years at baseline 2 to assess the relative importance of the associations of dietary quality and CVD for older adults compared to middle-aged adults Dietary variables were based on responses to the 24-hour dietary recall and the food frequency questionnaire administered at baseline and included a composite measure of dietary quality intakes of specific nutrients and usual consumption of foods from 19 food groups Baseline measures used as covariates included body mass index blood pressure serum cholesterol sociodemographic variables eg age race income occupation behavioral variables eg smoking alcohol consumption activity level and chronic health conditions CVD outcomes were determined from medical history questionnaires hospital records and death certificates Change in blood pressure between baseline and 10-year followup were examined as an outcome variable as well as a covariate in the association between diet and CVD
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R03HL048530 | NIH | None | httpsreporternihgovquickSearchR03HL048530 |