Ignite Creation Date:
2024-05-05 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00139958
Status:
COMPLETED
Last Update Posted:
2010-07-28
First Post:
2005-08-29
Brief Title:
Prognosis of Acute Coronary Syndrome in HIV-infected Patients
Sponsor:
Saint Antoine University Hospital
Organization:
Saint Antoine University Hospital
Study Overview
Official Title:
Prognosis After Acute Coronary Syndrome in HIV-infected Patients
Status:
COMPLETED
Status Verified Date:
2010-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objectives Evaluate differences for mortality morbidity and the cardiovascular risk factors between HIV and non-HIV patients with an acute coronary syndromes ACS after a 3-years follow up
Detailed Description:
Background There have been many cases of myocardial infarction reported in HIV-infected young adults treated with HAART Little is known to date concerning the outcome and prognostic factors of patients with acute coronary syndrome and HIV-infection
Methods Prospective cohort study to compare the evolution and prognosis between HIV and non-HIV patients with an ACS
Duration of the study Two years for including patients Three years of follow-up 100 HIV-patients with ACS and 200 non-HIV patients with ACS will be included in the study All patients will be included in the study from 30 Intensive Care Unit of Cardiology departments in France
Results To compare the incidence of total mortality cardiovascular mortality myocardial infarction sudden death cardiogenic shock fatal stroke morbidity non fatal myocardial infarction unstable angina recurrence of ischemia cardiac failure non fatal stroke and revascularization percutaneous coronary intervention coronary artery bypass graft surgery during a 3-year follow-up between HIV and non-HIV patients with ACS Univariate and multivariate analysis of predictive factors for cardiovascular events will be done
Methods Prospective cohort study to compare the evolution and prognosis between HIV and non-HIV patients with an ACS
Duration of the study Two years for including patients Three years of follow-up 100 HIV-patients with ACS and 200 non-HIV patients with ACS will be included in the study All patients will be included in the study from 30 Intensive Care Unit of Cardiology departments in France
Results To compare the incidence of total mortality cardiovascular mortality myocardial infarction sudden death cardiogenic shock fatal stroke morbidity non fatal myocardial infarction unstable angina recurrence of ischemia cardiac failure non fatal stroke and revascularization percutaneous coronary intervention coronary artery bypass graft surgery during a 3-year follow-up between HIV and non-HIV patients with ACS Univariate and multivariate analysis of predictive factors for cardiovascular events will be done
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None