Ignite Creation Date:
2025-12-24 @ 2:53 PM
Ignite Modification Date:
2026-03-01 @ 9:56 AM
Study NCT ID:
NCT00982059
Status:
COMPLETED
Last Update Posted:
2018-01-31
First Post:
2008-11-21
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Colorectal Cancer Screening for Cancer Survivors
Sponsor:
University Health Network, Toronto
Organization:
Study Overview
Official Title:
Colorectal Cancer Screening in Cancer Survivors Treated With Radiation Therapy
Status:
COMPLETED
Status Verified Date:
2018-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The risk of colorectal cancer (CRC) is significant among cancer survivors treated with abdominal radiation therapy (RT). Further, CRC is once of the few cancers for which there is effective screening. Although some expert groups recommend early CRC screening for patients with prior abdominal RT, the effectiveness of early screening is unknown. It is also unknown if radiation-induced CRC passes through a "pre-clinical" phase in which precancerous polyps are detectable and treatable prior to becoming invasive cancers. This study will evaluate whether screening will detect pre-invasive colorectal polyps among survivors treated with RT.
Detailed Description:
Cancer survivors meeting the COG criteria for CRC screening will undergo colonoscopy and removal of colorectal polyps. Documentation of polyp number, location and pathologic characteristics will be made. Clinical data information will also be collected at the time of patient enrollment.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: