Ignite Creation Date:
2024-05-06 @ 1:37 AM
Last Modification Date:
2024-10-26 @ 11:07 AM
Study NCT ID:
NCT01857336
Status:
COMPLETED
Last Update Posted:
2020-09-25
First Post:
2013-05-16
Brief Title:
G-CSF Moblized Peripheral Harvest for Poor Engraftment After Stem Cell Transplantation
Sponsor:
Peking University Peoples Hospital
Organization:
Peking University Peoples Hospital
Study Overview
Official Title:
Infusion of Recombinant Human Granulocyte Colony Stimulating Factor Mobilized Peripheral Harvest for Poor Engraftment After Hematopoietic Stem Cell Transplantation
Status:
COMPLETED
Status Verified Date:
2020-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Poor graft function PGF is a common complication after allogeneic stem cell transplantation which was associated with high mortality The pathogenesis fo PGF was poorly understood Infusion of donor peripheral cell harvest was effective for some patients with PGF in our preliminary study This present study aimed to explore the efficacy of peripheral cell harvest for poor graft function
Detailed Description:
Poor graft function PGF is a common complication after allogeneic stem cell transplantation which was associated with high mortality The pathogenesis fo PGF was poorly understood Infusion of donor peripheral cell harvest was effective for some patients with PGF in our preliminary studyThe peripheral cell harvest was aphaeresis on the fourth or fifth day after mobilization with recombinant human granulocyte colony stimulating factor Hematogical response was assessed at 30 days after infusion Good response was defined as neutrophil 10109l without G-CSF support for at least 3 consecutive days and persistent platelet 20109l without transfusion for at least 7 days Otherwise poor response was defined
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None