Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005248
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-05-25
Brief Title:
Adiposity and Fat Patterning in Black Americans
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2002-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine the relationships of obesity and fat patterning with morbidity and mortality in Black Americans
Detailed Description:
BACKGROUND
Studies have shown that fat patterning is an important risk factor for diabetes and possibly cardiovascular diseases The Secretarys Task Force on Black and Minority Health in 1985 concluded that diabetes and cardiovascular diseases were among the six causes of death that contribute most to the disparity in death rates between Blacks and whites yet the relationship of fat patterning with these diseases was largely unstudied in Blacks Since there are known racial differences in growth rates body proportions and adiposity it cannot be assumed that studies done on whites are applicable to Blacks
The Charleston Heart Study began in 1960 with the examination of a random sample of 2181 residents of Charleston County Approximately one-third of the sample was Black The cohort was re-examined in 1963-1964 1974-1975 and 1984-1985 and the fifth recall involving physical examination electrocardiogram echocardiograph plasma glucose and lipid assays physical disability assessment and 24-hour Holter monitoring was completed In the 1963-1964 recall 102 high socioeconomic status Black men were added to the cohort Also in the 1963-1964 recall a battery of anthropometric measurements were taken on about half the cohort and these measurements and others were included in the 1987-1988 recall Thus height weight reported weight at age 25 circumference of the chest at inhale and exhale circumference at the umbilicus and mid-arm circumference were available on the same individuals from the 1963-1964 and the 1987-1988 examinations In addition skinfolds at the triceps biceps subscapular suprailiac and lower thigh and circumference at the hips were measured in the latter recall The fifth examination was completed in 1989 under separate NHLBI grant support
DESIGN NARRATIVE
Cross-sectional relationships were estimated between anthropometric measures of body dimensions such as abdominal central and upper body fat patterning and total adiposity and the dependent variables of diabetes blood pressure plasma lipids and glucose and left ventricular wall thickness Anthropometric predictors of diabetes blood pressure plasma lipids and glucose and left ventricular wall thickness were identified over a 24 year interval Anthropometric predictors of survival were identified over a 25 year period with reference to mortality for coronary heart disease cardiovascular disease and all-cause mortality Body dimensions were described by race and sex groups and changes in the shapes of individuals over a 24 year interval were examined The importance of changes in anthropometric measurements with aging was determined for the prediction of diabetes blood pressure plasma lipids and glucose left ventricular wall thickness mortality from all causes and from coronary heart disease and cardiovascular disease
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Studies have shown that fat patterning is an important risk factor for diabetes and possibly cardiovascular diseases The Secretarys Task Force on Black and Minority Health in 1985 concluded that diabetes and cardiovascular diseases were among the six causes of death that contribute most to the disparity in death rates between Blacks and whites yet the relationship of fat patterning with these diseases was largely unstudied in Blacks Since there are known racial differences in growth rates body proportions and adiposity it cannot be assumed that studies done on whites are applicable to Blacks
The Charleston Heart Study began in 1960 with the examination of a random sample of 2181 residents of Charleston County Approximately one-third of the sample was Black The cohort was re-examined in 1963-1964 1974-1975 and 1984-1985 and the fifth recall involving physical examination electrocardiogram echocardiograph plasma glucose and lipid assays physical disability assessment and 24-hour Holter monitoring was completed In the 1963-1964 recall 102 high socioeconomic status Black men were added to the cohort Also in the 1963-1964 recall a battery of anthropometric measurements were taken on about half the cohort and these measurements and others were included in the 1987-1988 recall Thus height weight reported weight at age 25 circumference of the chest at inhale and exhale circumference at the umbilicus and mid-arm circumference were available on the same individuals from the 1963-1964 and the 1987-1988 examinations In addition skinfolds at the triceps biceps subscapular suprailiac and lower thigh and circumference at the hips were measured in the latter recall The fifth examination was completed in 1989 under separate NHLBI grant support
DESIGN NARRATIVE
Cross-sectional relationships were estimated between anthropometric measures of body dimensions such as abdominal central and upper body fat patterning and total adiposity and the dependent variables of diabetes blood pressure plasma lipids and glucose and left ventricular wall thickness Anthropometric predictors of diabetes blood pressure plasma lipids and glucose and left ventricular wall thickness were identified over a 24 year interval Anthropometric predictors of survival were identified over a 25 year period with reference to mortality for coronary heart disease cardiovascular disease and all-cause mortality Body dimensions were described by race and sex groups and changes in the shapes of individuals over a 24 year interval were examined The importance of changes in anthropometric measurements with aging was determined for the prediction of diabetes blood pressure plasma lipids and glucose left ventricular wall thickness mortality from all causes and from coronary heart disease and cardiovascular disease
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 5R01HL042305 | NIH | None | httpsreporternihgovquickSearch5R01HL042305 |