Ignite Creation Date:
2024-05-06 @ 1:31 AM
Last Modification Date:
2024-10-26 @ 11:04 AM
Study NCT ID:
NCT01820104
Status:
COMPLETED
Last Update Posted:
2013-05-03
First Post:
2013-03-17
Brief Title:
Effects of Lansoprazole on Sitagliptin Glucose-lowering Ability in Healthy Males a Randomised Crossover Study
Sponsor:
Xijing Hospital
Organization:
Xijing Hospital
Study Overview
Official Title:
Effects of Lansoprazole on Sitagliptin Glucose-lowering Ability in Healthy Males
Status:
COMPLETED
Status Verified Date:
2013-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Oral hypoglycemic medications sometimes do not control type 2 diabetes well Proton pump inhibitors PPIs as adjunctive therapy might improve diabetes control and could enhance the hypoglycemic activity of DPP4 but there is little clinical data on efficacy of this therapeutic strategy The investigators sought to examine the effect of PPI lansoprazole DPP-4 inhibitor sitagliptin and their combination therapy on insulin and glucose regulation in healthy subjects in oral glucose tolerance OGTT
Detailed Description:
Oral hypoglycemic medications sometimes do not control type 2 diabetes well Proton pump inhibitors PPIs as adjunctive therapy might improve diabetes control and could enhance the hypoglycemic activity of DPP4 but there is little clinical data on efficacy of this therapeutic strategy We sought to examine the effect of PPI lansoprazole DPP4 sitagliptin and their combination therapy on insulin and glucose regulation in healthy subjects in oral glucose tolerance OGTT
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None