Ignite Creation Date:
2024-05-06 @ 1:30 AM
Last Modification Date:
2024-10-26 @ 11:05 AM
Study NCT ID:
NCT01822106
Status:
UNKNOWN
Last Update Posted:
2013-04-02
First Post:
2013-03-24
Brief Title:
Randomized Double Blind Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease GERD
Sponsor:
China Medical University Hospital
Organization:
China Medical University Hospital
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2013-03
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
GERD is due to gastric content reflux to esophagus cause symptom and complication including intra-esophagus such as reflux esophagitis and extra-esophagus such as cough etc Because the changes of dietary habit and improvement of examination skill and data analysis the prevalence of GERD increased 25 multiple from 1995 to 2002 and suggesting the prevalence is 25 in Taiwan community
Although proton pump inhibitor PPI can inhibit gastric acid secretion relief symptom and enhancing repair of esophageal damage therefore PPI is a main drug for the treatment of GRED but because of PPI has disadvantage of poor compliance and slow gastric empty time and hypersensitivity and about 40-50 of GERD patients is inefficacy In addition PPI produces bone fracture community pneumonia and diarrhea in patient with long-term use
Wu-Chu-Yu tang consists of Evodia fargesii Dode Evodia Fruit Panax ginseng C Ginseng Ziziphus jujube Mill Chinses Date Zingiber officinale Rosee Fresh Ginger According to I-Fang-Chi-Chieh and Shanghonzobinglun recordings that Wu-Chu-Yu tang can treat vomiting and also can relax gastric tonicity and can enhance peristalsis of stomach
Therefore the purpose of the present study was to investigate the efficacy of Wu-Chu-Yu tang on GRED and this effect of Wu-Chu-Yu tang compared to PPI Omeprazole
Although proton pump inhibitor PPI can inhibit gastric acid secretion relief symptom and enhancing repair of esophageal damage therefore PPI is a main drug for the treatment of GRED but because of PPI has disadvantage of poor compliance and slow gastric empty time and hypersensitivity and about 40-50 of GERD patients is inefficacy In addition PPI produces bone fracture community pneumonia and diarrhea in patient with long-term use
Wu-Chu-Yu tang consists of Evodia fargesii Dode Evodia Fruit Panax ginseng C Ginseng Ziziphus jujube Mill Chinses Date Zingiber officinale Rosee Fresh Ginger According to I-Fang-Chi-Chieh and Shanghonzobinglun recordings that Wu-Chu-Yu tang can treat vomiting and also can relax gastric tonicity and can enhance peristalsis of stomach
Therefore the purpose of the present study was to investigate the efficacy of Wu-Chu-Yu tang on GRED and this effect of Wu-Chu-Yu tang compared to PPI Omeprazole
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None