Ignite Creation Date:
2024-05-06 @ 1:29 AM
Last Modification Date:
2024-10-26 @ 11:05 AM
Study NCT ID:
NCT01828710
Status:
COMPLETED
Last Update Posted:
2022-07-25
First Post:
2013-03-21
Brief Title:
Myo-inositol on Human Semen Parameters
Sponsor:
AGUNCO Obstetrics and Gynecology Centre
Organization:
AGUNCO Obstetrics and Gynecology Centre
Study Overview
Official Title:
Effect of Treatment With Myo-inositol on Human Semen Parameters in Patients Undergoing IVF Cycles
Status:
COMPLETED
Status Verified Date:
2022-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Many clinical evidences suggest that Myo-inositol plays a crucial role in human reproduction Also it was shown that Myo-inositol concentration in the seminiferous tubules was higher than in serum and interestingly it was increasing through the epididymis and the deferent duct mining that sperm cell before ejaculation are stored in a medium highly enriched in myo-inositol
Starting from this evidences the investigators hypothesized that myo-inositol may be a possible factor able to improve the semen parameters of samples used in in vitro fertilization cycles
Starting from this evidences the investigators hypothesized that myo-inositol may be a possible factor able to improve the semen parameters of samples used in in vitro fertilization cycles
Detailed Description:
Samples of seminal fluid were obtained from two groups of patients undergoing to an IVF cycle healthy normospermic subjects and subjects with oligoasthenoteratospermia OAT 15 milml
Semen volume spermatozoa number and motility were evaluated during the initial semen analysis and after density gradient separation method These parameters were evaluated before and after the administration of 4000mgdie of myo-inositol associated to 400 µg of folic acid Inofolic lolipharma Rome for three months
A third group of healthy normospermic subject were traded with 400 µg of folic acid for three months and was consider a control group
Semen volume spermatozoa number and motility were evaluated during the initial semen analysis and after density gradient separation method These parameters were evaluated before and after the administration of 4000mgdie of myo-inositol associated to 400 µg of folic acid Inofolic lolipharma Rome for three months
A third group of healthy normospermic subject were traded with 400 µg of folic acid for three months and was consider a control group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None