Ignite Creation Date:
2024-05-05 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 9:13 AM
Study NCT ID:
NCT00134446
Status:
UNKNOWN
Last Update Posted:
2005-10-30
First Post:
2005-08-23
Brief Title:
Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder
Sponsor:
White River Junction Veterans Affairs Medical Center
Organization:
White River Junction Veterans Affairs Medical Center
Study Overview
Official Title:
A Prospective Double Blind Randomized Placebo Controlled Trial of Repetitive Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder
Status:
UNKNOWN
Status Verified Date:
2005-03
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine if transcranial magnetic stimulation at 1 HZ to the right frontal cortex will decrease the symptoms of post-traumatic stress disorder PTSD
Detailed Description:
Post-traumatic stress disorder PTSD is a psychiatric disorder that is common in the general population PTSD symptoms include re-experiencing the traumatic event avoidance of reminders of the trauma and increased arousal The primary treatments of PTSD are psychotherapy and antidepressant medications While both are effective many patients continue to have significant symptoms Repetitive Transcranial Magnetic Stimulation rTMS is a new research and treatment modality that uses a small powerful electromagnet to directly stimulate the brain This stimulation may increase or decrease brain activity The treatments have been shown to be effective in other disorders such as depression Initial treatment of patients with PTSD using rTMS has been hopeful This study is the first randomized controlled trial to examine the efficacy of rTMS for PTSD
This study would be the first randomized placebo controlled trial to examine the efficacy of Transcranial Magnetic Stimulation rTMS for PTSD The primary hypothesis is that there will be significant improvement in the patients PTSD symptoms from pre-treatment to post-treatment with rTMS A secondary hypothesis is that the patients co-morbid depressive symptoms will improve from pre-treatment to post-treatment Forty subjects with PTSD will be recruited from the White River Junction VAMC Patients will be randomly assigned to receive either active rTMS or sham rTMS Patients staff performing the treatments and staff completing the assessments will all be blinded to active or sham treatment
This study would be the first randomized placebo controlled trial to examine the efficacy of Transcranial Magnetic Stimulation rTMS for PTSD The primary hypothesis is that there will be significant improvement in the patients PTSD symptoms from pre-treatment to post-treatment with rTMS A secondary hypothesis is that the patients co-morbid depressive symptoms will improve from pre-treatment to post-treatment Forty subjects with PTSD will be recruited from the White River Junction VAMC Patients will be randomly assigned to receive either active rTMS or sham rTMS Patients staff performing the treatments and staff completing the assessments will all be blinded to active or sham treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Hitchcock Foundation | None | None | None |