Ignite Creation Date:
2024-05-06 @ 1:28 AM
Last Modification Date:
2024-10-26 @ 11:04 AM
Study NCT ID:
NCT01814358
Status:
WITHDRAWN
Last Update Posted:
2023-10-02
First Post:
2013-03-15
Brief Title:
Whey Protein Effects on Gycemic Control and Vascular Function
Sponsor:
University of California Los Angeles
Organization:
University of California Los Angeles
Study Overview
Official Title:
Effects of Pre-meal Whey Protein Ingestion on Daily Glycemic Control and Oxidative Stress Mediated Postprandial Inflammation and Vascular Dysfunction Evoked by Consumption of a High-glycemic Meal
Status:
WITHDRAWN
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Risk for heart and blood vessel diseases is increased when blood sugar rises Blood vessel dysfunction is common to such diseases Elevated blood sugar after eating promotes blood vessel dysfunction Dietary factors other than carbohydrates influence rises and falls in blood sugar Dietary protein is associated with improved blood sugar control Whey protein effectively blunts the rise in blood sugar after consuming a carbohydrate rich drinkmeal in normal weight and obese adults This study will investigate the efficacy of drinking a whey protein beverage prior to eating for improved daily blood sugar control in normal weight and obese adults in the real world Also the study will test this dietary approach to reduce blood vessel dysfunction associated with eating a meal that causes blood sugar to rise 24 normal weight and 24 obese men and premenopausal women 18-50y will participate Subjects will wear a sensor to monitor daily blood sugar changes in response to their typically consumed diets for 2 days Subjects will report to the UCLA CTRC the morning after the monitoring period for measurement of blood vessel function after eating a breakfast cereal meal Blood samples will be obtained before and after the meal to measure relevant health markers Subjects will repeat the 2-day diet and breakfast cereal meal challenge after a week or more and will consume either a chocolate flavored 1 whey protein or 2 gelatin protein control shake prior to each meal Neither subjects nor researchers will know which protein double blind Subjects will receive the alternate protein intervention after another week or more crossover We think drinking the protein shake prior to meals will reduce daily blood sugar rises and falls after eating and blunt the blood vessel dysfunction that results from eating the breakfast cereal
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None