Ignite Creation Date:
2024-05-05 @ 11:46 AM
Last Modification Date:
2024-10-26 @ 9:12 AM
Study NCT ID:
NCT00123162
Status:
COMPLETED
Last Update Posted:
2015-12-23
First Post:
2005-07-20
Brief Title:
Viagra in the Treatment of Primary Dysmenorrhea
Sponsor:
Milton S Hershey Medical Center
Organization:
Milton S Hershey Medical Center
Study Overview
Official Title:
Sildenafil Citrate in the Treatment of Primary Dysmenorrhea
Status:
COMPLETED
Status Verified Date:
2015-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary hypothesis is that a 100mg single dose of sildenafil citrate Viagra will have a higher improvement rate when compared to placebo in the treatment of moderate to severe primary dysmenorrhea
Detailed Description:
It is well established that excess prostaglandin production in primary dysmenorrhea leads to ischemia of the uterine muscle which consequently causes pelvic pain A large number of drugs have been studied for pain relief in dysmenorrhea patients with non-steroid anti-inflammatory drugs NSAIDS being the most effective with the overall success rate of more than 75 Sildenafil citrate Viagra is an inhibitor that augments the vasodilatory effects of nitric oxide by preventing the degradation of Cyclic guanosine monophosphate cGMP in the uterine muscle Sildenafil is commonly used in the treatment of male erectile dysfunction pulmonary hypertension in children and adults and in vitro fertilization To date it has not been used in the treatment of primary dysmenorrhea
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None