Ignite Creation Date:
2024-05-06 @ 1:25 AM
Last Modification Date:
2024-10-26 @ 11:03 AM
Study NCT ID:
NCT01800786
Status:
COMPLETED
Last Update Posted:
2017-06-06
First Post:
2013-02-23
Brief Title:
Memory Consolidation in Obstructive Sleep Apnea
Sponsor:
Brigham and Womens Hospital
Organization:
Brigham and Womens Hospital
Study Overview
Official Title:
Memory Consolidation in Obstructive Sleep Apnea
Status:
COMPLETED
Status Verified Date:
2017-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The overarching goal of the research proposed here is to test the hypothesis i that the pathophysiological mechanisms of OSA lead to deterioration in sleep-dependent memory consolidation across memory systems with the genetic marker APOε4 as a modulator and ii that CPAP can reverse some or all of these measured memory deficits
In addition we are exploring which aspects of OSA eg changes in sleep architecture measures of hypoxemia or the EEG power spectrum most likely impact sleep-dependent memory processingTo this end we are using specific cognitive tasks for which sleep-dependent memory consolidation processes have previously been demonstrated by our group and others In addition we are carrying out quantitative EEG power spectral analyses to delineate abnormal functioning of brain regions with more precision
In addition we are exploring which aspects of OSA eg changes in sleep architecture measures of hypoxemia or the EEG power spectrum most likely impact sleep-dependent memory processingTo this end we are using specific cognitive tasks for which sleep-dependent memory consolidation processes have previously been demonstrated by our group and others In addition we are carrying out quantitative EEG power spectral analyses to delineate abnormal functioning of brain regions with more precision
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| K23HL103850-01 | NIH | None | httpsreporternihgovquickSearchK23HL103850-01 |