Ignite Creation Date:
2024-05-06 @ 1:24 AM
Last Modification Date:
2024-10-26 @ 11:04 AM
Study NCT ID:
NCT01806428
Status:
COMPLETED
Last Update Posted:
2013-10-22
First Post:
2013-03-06
Brief Title:
Activated Protein C and Microcirculation
Sponsor:
Università Politecnica delle Marche
Organization:
Università Politecnica delle Marche
Study Overview
Official Title:
THE Activated Protein C aPC TREATMENT IMPROVES MICROCIRCULATION IN SEVERE SEPSIS SEPTIC SHOCK SYNDROME
Status:
COMPLETED
Status Verified Date:
2013-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objective to test the hypothesis that recombinant activated protein C aPC therapy improves the microcirculation of severe septic patients
Design Prospective open study Setting University 12-beds intensive care unit Patients Septic patients with at least two sepsis-induced organ failures occurring within 48 hours of the onset of sepsis were included in a one year period
Interventions Patients who had no contraindication to aPC administration received aPC at a dose of 24 mcgkgh for 96 hours Patients with contraindications to aPC infusion were considered as controls
Design Prospective open study Setting University 12-beds intensive care unit Patients Septic patients with at least two sepsis-induced organ failures occurring within 48 hours of the onset of sepsis were included in a one year period
Interventions Patients who had no contraindication to aPC administration received aPC at a dose of 24 mcgkgh for 96 hours Patients with contraindications to aPC infusion were considered as controls
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None