Ignite Creation Date:
2024-05-06 @ 1:23 AM
Last Modification Date:
2024-10-26 @ 11:03 AM
Study NCT ID:
NCT01799655
Status:
COMPLETED
Last Update Posted:
2014-05-06
First Post:
2013-02-06
Brief Title:
Does Vitamin D Deficiency Associated With Hypercoagulability Increased Thrombin Generation
Sponsor:
HaEmek Medical Center Israel
Organization:
HaEmek Medical Center Israel
Study Overview
Official Title:
Does Vitamin D Deficiency Associated With Hypercoagulability Increased Thrombin Generation
Status:
COMPLETED
Status Verified Date:
2013-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Cardiovascular disease is the most common cause of mortality and morbidity worldwide Recently a growing body of evidence has identified Vitamin D deficiency as a potential risk factor for cardiovascular disease Therefore there is an increasing interest to explore the mechanism in which vitamin D deficiency affect the cardiovascular system
The investigators want to examine the relationship between serum vitamin D levels and the coagulation status in the subjects The applied the calibrated automated thrombogram CAT to assess thrombin generation in plasma as a measure of overall thrombotic activity and thus to suggest a mechanism that may explain the link between vitamin D deficiency and cardiovascular disease
Our study population are going to include 100 patients from the internal departments in Emek hospital who present with chest pain but without acute coronary syndrome ACS The investigators will take blood samples from the subjects to measure the serum vitamin D levels and the generation of thrombin The patients will be divided into four groups according to the level of vitamin D to evaluate the effect of vitamin D levels in the blood on coagulability and thrombotic activity in these patients
The investigators want to examine the relationship between serum vitamin D levels and the coagulation status in the subjects The applied the calibrated automated thrombogram CAT to assess thrombin generation in plasma as a measure of overall thrombotic activity and thus to suggest a mechanism that may explain the link between vitamin D deficiency and cardiovascular disease
Our study population are going to include 100 patients from the internal departments in Emek hospital who present with chest pain but without acute coronary syndrome ACS The investigators will take blood samples from the subjects to measure the serum vitamin D levels and the generation of thrombin The patients will be divided into four groups according to the level of vitamin D to evaluate the effect of vitamin D levels in the blood on coagulability and thrombotic activity in these patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None