Ignite Creation Date:
2024-05-06 @ 1:23 AM
Last Modification Date:
2024-10-26 @ 11:03 AM
Study NCT ID:
NCT01794871
Status:
UNKNOWN
Last Update Posted:
2013-02-22
First Post:
2013-02-16
Brief Title:
The Histological Analysis in Renal Transplantation Patients With Deterioration of Graft Function
Sponsor:
Shanghai Zhongshan Hospital
Organization:
Shanghai Zhongshan Hospital
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2013-02
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Identify the cause of chronic allograft dysfunction using a combination of comprehensive clinical and histologic information in Chinese renal transplant recipients then to identify the position of CNI nephrotoxicity in CADChronic allograft dysfunction reflects the dual impact of both immunologic and nonimmunologic primarily calcineurin inhibitor CNInephrotoxicity injury In previous CNI nephrotoxicity is overstated and considered one of the major causes of CAD however recently there has been found most death-censored graft losses to be the result of alloimmune or autoimmune injury with only a minority of cases attributable to CNI toxicity Unfortunately Situation of objective CNI toxicity in CAD in China is not well analyzed To improve perception of Neo safety with more local evidence we want to do a retrospective study to identify the cause of chronic allograft dysfunction using a combination of comprehensive clinical and histologic information in Chinese renal transplantation recipients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None