Ignite Creation Date:
2024-05-06 @ 1:19 AM
Last Modification Date:
2024-10-26 @ 11:02 AM
Study NCT ID:
NCT01788267
Status:
COMPLETED
Last Update Posted:
2019-05-28
First Post:
2013-02-05
Brief Title:
Bone Microarchitecture in Young Cystic Fibrosis Patients
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Evaluation of the Bone Microarchitecture in a Young Cystic Fibrosis Patients Using High-Resolution Peripheral Quantitative Computed Tomography
Status:
COMPLETED
Status Verified Date:
2015-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with cystic fibrosis are at risk of developing low bone mineral density BMD potentially leading to pathological fractures at adult age Recent data from our center and others have suggested that low BMD could be observed very early in life However quantitative bone abnormalities found out by Dual X-ray absorptiometry DXA need to be confronted to qualitative evaluation of bone microarchitecture surrogate of bone strength
High-Resolution peripheral quantitative computed tomography HR-pQCT is a recent technology with very high spatial resolution Images obtained with this technic are considered as virtual bone biopsies It enables an accurate bones cortical and trabecular surfaces exploration in a three-dimensional manner and therefore provides informations on bone microarchitecture as well as bone density
The aim of this study is to evaluate bone microarchitecture of paediatric patients matched to sex-age-pubertal status-healthy volunteers In the meantime biological markers will be collected and DXA Dual-energy x-ray absorptiometry will be performed in order to explore potential correlations HR-pQCT parameters
High-Resolution peripheral quantitative computed tomography HR-pQCT is a recent technology with very high spatial resolution Images obtained with this technic are considered as virtual bone biopsies It enables an accurate bones cortical and trabecular surfaces exploration in a three-dimensional manner and therefore provides informations on bone microarchitecture as well as bone density
The aim of this study is to evaluate bone microarchitecture of paediatric patients matched to sex-age-pubertal status-healthy volunteers In the meantime biological markers will be collected and DXA Dual-energy x-ray absorptiometry will be performed in order to explore potential correlations HR-pQCT parameters
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None