Ignite Creation Date:
2024-05-05 @ 11:45 AM
Last Modification Date:
2024-10-26 @ 9:12 AM
Study NCT ID:
NCT00121524
Status:
COMPLETED
Last Update Posted:
2015-05-29
First Post:
2005-07-13
Brief Title:
Effects of Epinephrine and Intravenous IV Needle on Cardiopulmonary Resuscitation CPR Outcome
Sponsor:
Petter Andreas Steen
Organization:
University of Oslo
Study Overview
Official Title:
Effects of Epinephrine and IV Needle on CPR Outcome
Status:
COMPLETED
Status Verified Date:
2015-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Intravenous epinephrine has been part of the guidelines for cardiopulmonary resuscitation since the start It improves outcome in animal studies but has never been investigated in a controlled study in humans Epidemiologic data indicate that it is an independent negative predictor for survival If this is true in a controlled randomized study it could be due to effects of the drug itself or more likely due to reduced quality of chest compressions and ventilations due to the time spent on placing an IV needle and injecting drugs
Detailed Description:
In a randomized controlled study of all out-of-hospital cardiac arrest patients in Oslo Norway half the patients are treated according to the international guidelines for advanced CPR and the other half according to the same guidelines except for no IV needle or drugs are given until 5 minutes after eventual return of spontaneous circulation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None