Ignite Creation Date:
2024-05-05 @ 11:45 AM
Last Modification Date:
2024-10-26 @ 9:13 AM
Study NCT ID:
NCT00129883
Status:
COMPLETED
Last Update Posted:
2005-09-27
First Post:
2005-08-11
Brief Title:
Adherence to Guidelines for Antibiotic Use in Respiratory Infections at Hospitals
Sponsor:
Radboud University Medical Center
Organization:
Radboud University Medical Center
Study Overview
Official Title:
Prevention of Antimicrobial Resistance in Hospitals Promoting Appropriate Use of Antibiotics in Hospital Departments of Internal and Pulmonary Medicine
Status:
COMPLETED
Status Verified Date:
2002-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to test a strategy to improve the quality of antibiotic use in lower respiratory tract infections LRTIs at hospitals Therefore a multifaceted intervention strategy is compared to a control strategy and the effectiveness and feasibility of the intervention is assessed
Detailed Description:
Improving processes of care in patients with hospital LRTI has been related to better patient outcome Inappropriate use of antibiotics has contributed to the emergence and spread of drug-resistant micro organisms and increased treatment costs International guidelines provide recommendations for the initial evaluation and management of LRTI including advice on judicious antibiotic therapy Nonetheless studies have demonstrated a wide variability in adherence to these guidelines
To implement key recommendations in clinical practice various strategies have been used with mixed results Perhaps the most important aspect of choosing a potentially effective intervention is that the choice of intervention should be based upon assessment of potential barriers in the target group Many intervention studies are flawed by failing to control for secular trends
The investigators performed a cluster randomised controlled trial to study the effect of a multifaceted intervention strategy on the quality of antibiotic use for LRTI Their intervention was tailored to the areas most in need for improvement and took perceived barriers in the target group into consideration at the individual hospital level
To implement key recommendations in clinical practice various strategies have been used with mixed results Perhaps the most important aspect of choosing a potentially effective intervention is that the choice of intervention should be based upon assessment of potential barriers in the target group Many intervention studies are flawed by failing to control for secular trends
The investigators performed a cluster randomised controlled trial to study the effect of a multifaceted intervention strategy on the quality of antibiotic use for LRTI Their intervention was tailored to the areas most in need for improvement and took perceived barriers in the target group into consideration at the individual hospital level
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| ZonMw grant no 23000024 | None | None | None |