Ignite Creation Date:
2024-05-06 @ 1:13 AM
Last Modification Date:
2024-10-26 @ 11:01 AM
Study NCT ID:
NCT01769053
Status:
TERMINATED
Last Update Posted:
2018-07-26
First Post:
2012-12-18
Brief Title:
Variable Pressure Support Trial
Sponsor:
Technische Universität Dresden
Organization:
Technische Universität Dresden
Study Overview
Official Title:
International Multicenter Randomized Controlled Open Trial on Variable vs Non-Variable Pressure Support for Weaning From Mechanical Ventilation
Status:
TERMINATED
Status Verified Date:
2018-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Rate of recruitment
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ViPS
Brief Summary:
In 2008 a new ventilation strategy termed variable Pressure Support ventilation PSV was introduced which is able to increase the variability of the respiratory pattern independent from the inspiratory effort In experimental lung injury variable PSV was found to improve gas exchange and decrease the inspiratory effort while reducing alveolar edema and inflammatory infiltration compared to conventionalnon-variable PSV Importantly variable PSV reduced peak airway pressure and respiratory system elastance in a variability dependent mannerIn addition preliminary observations suggest that variable PSV can reduce the work of breathing and improve patient comfort but it is not known whether this new ventilatory strategy is able to speed the weaning from mechanical ventilation
Since variable PSV can reduce the mean pressure support it may lead to a faster reduction of pressure support and therefore a shorter weaning period than conventional PSV
The hypothesis of this study is that variable pressure support ventilation reduces the duration of mechanical ventilation to non-variable conventional pressure support ventilation
Since variable PSV can reduce the mean pressure support it may lead to a faster reduction of pressure support and therefore a shorter weaning period than conventional PSV
The hypothesis of this study is that variable pressure support ventilation reduces the duration of mechanical ventilation to non-variable conventional pressure support ventilation
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None