Ignite Creation Date:
2024-05-05 @ 11:45 AM
Last Modification Date:
2024-10-26 @ 9:13 AM
Study NCT ID:
NCT00129012
Status:
COMPLETED
Last Update Posted:
2016-02-25
First Post:
2005-08-09
Brief Title:
Self-Gated Breath-Hold Technique for Helical Tomotherapy in Patients With Non-Small Cell Lung Cancer
Sponsor:
AHS Cancer Control Alberta
Organization:
AHS Cancer Control Alberta
Study Overview
Official Title:
Self-Gated Breath-Hold Technique for Helical Tomotherapy in Patients With Non-Small Cell Lung Cancer A Feasibility Study
Status:
COMPLETED
Status Verified Date:
2012-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Non-small cell lung cancer NSCLC is a disease that often cannot be surgically operated on As a result treating the tumor with radiation has become the main standard of treatment Radiation therapy though is limited by various factors including the difficulty in properly imaging the lung tumor since the lung can move up to 4 cm between breathing in and out Consequently a radiation oncologist must consider a larger area of the lung to treat with radiation - increasing the amount of normal tissue exposed to harmful rays and therefore leading to increased side-effects Two techniques being explored into improving tumor management while minimizing the side effects in NSCLC are breath-held gating and tomotherapy Breath-held gating is a technique for consistently imaging the tumor at the right moment in a patients breathing cycle - decreasing the normal tissue exposed to harmful radiation Tomotherapy a new technique in delivering radiation will further allow the investigators to focus treatment on the tumor and exclude more normal tissues Therefore they hope that these methods will prove to be a better way in treating people with NSCLC
Detailed Description:
Non-small cell lung cancer NSCLC is a disease that often presents as an unresectable tumor As a result radiotherapy is the main standard of treatment Unfortunately radiotherapy is limited by several factors including that the lung can move up to 4 cm between inspiration and expiration As a result a radiation oncologist often has to widen his treatment field to include for this motion This leads to greater side effects for the patient Two techniques that are being explored to improve the tumor control of radiotherapy and to minimize side effects to normal tissues in NSCLC treatment include breath-held gating and tomotherapy Breath-held gating will allow the investigators to treat patients at the right moment in their breathing cycle consistently - minimizing the normal tissue exposed to radiation In addition both gated breathing and tomotherapy will allow the investigators to create a more refined tumor volume treated and exclude more of the normal tissues Consequently they hope these methods will prove to be a better way to treat patients with non-resectable NSCLC
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None