Ignite Creation Date:
2024-05-06 @ 1:06 AM
Last Modification Date:
2024-10-26 @ 10:59 AM
Study NCT ID:
NCT01734863
Status:
WITHDRAWN
Last Update Posted:
2016-01-12
First Post:
2012-11-19
Brief Title:
Post-operative Radiotherapy in Poor Responders Ewings Sarcoma Patients
Sponsor:
Childrens Cancer Hospital Egypt 57357
Organization:
Childrens Cancer Hospital Egypt 57357
Study Overview
Official Title:
Post-operative Radiotherapy Randomization in Poor Responders Ewings Sarcoma Patients
Status:
WITHDRAWN
Status Verified Date:
2012-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Local recurrence after surgical resection is a complex phenomenon An important predictive factor is the response to chemotherapy Central site of disease may be a second independent predictive factor Lin et al 2007 Patients with more than 10 viable tumour cells at surgery following neo-adjuvant chemotherapy had a less favourable outcome with an Event-free Survival EFS of 47 after 10 years Patients with good histological response 10 viable tumour cells after chemotherapy alone had a prognosis of about 70 after 10 years
However further studies are necessary to determine the merit of adjuvant radiation for high-risk patients poor responders Taking into consideration that the toxicity and morbidity of combined surgery and radiation is greater than either alone and must be closely monitored
However further studies are necessary to determine the merit of adjuvant radiation for high-risk patients poor responders Taking into consideration that the toxicity and morbidity of combined surgery and radiation is greater than either alone and must be closely monitored
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None