Ignite Creation Date:
2024-05-05 @ 11:44 AM
Last Modification Date:
2024-10-26 @ 9:13 AM
Study NCT ID:
NCT00125216
Status:
COMPLETED
Last Update Posted:
2014-04-07
First Post:
2005-07-27
Brief Title:
Evaluation of the Effects of Response Elaboration Training for Aphasia
Sponsor:
US Department of Veterans Affairs
Organization:
VA Office of Research and Development
Study Overview
Official Title:
Evaluation of the Effects of Response Elaboration Training for Aphasia
Status:
COMPLETED
Status Verified Date:
2014-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to evaluate the effects of Response Elaboration Training RET which is a speechlanguage therapy for aphasia The study is designed to determine whether verbal language production improves in terms of content and length of utterances as a result of treatment
Detailed Description:
Detailed Description
Extended description of the protocol including information not already contained in other fields such as comparisons studied
Example
Sudden out-of-hospital cardiac arrest OOH-CA remains a significant cause of death in spite of recent declines in overall mortality from cardiovascular disease Existing methods of emergency resuscitation are inadequate due to time delays inherent in the transport of a trained responder with defibrillation capabilities to the side of the OOH-CA victim Existing Emergency Medical Services EMS systems typically combine paramedic Emergency Medical Technician EMT services with some level of community involvement such as bystander cardiopulmonary resuscitation CPR training Some communities include automated external defibrillators AEDs at isolated sites or in mobile police or fire vehicles A comprehensive integrated community approach to treatment with AEDs would have community units served by these volunteer non-medical responders who can quickly identify and treat a patient with OOH-CA Such an approach is termed Public Access Defibrillation PAD
Comparisons Community units trained and equipped to provide public access defibrillation in addition to optimal standard care compared to community units trained to provide optimal standard care recognition of out-of-hospital cardiac arrest 911 access and cardiopulmonary resuscitation
The purpose of the proposed research is to thoroughly evaluate the effects of Response Elaboration Training RET with persons with aphasia Specifically the proposed research investigation is designed to delineate the outcomes that may be expected with RET The study is also designed to improve outcomes in the area of stimulus generalization effects of treatment by testing a modification of RET designed to facilitate generalization The specific experimental questions to be addressed are as follows
Will RET result in increased production of correct information units and increased length and changes in composition of utterances as measured in trained and untrained picture descriptions story retells conversations with significant othersfamily membersfriends and personal recounts
Will modification and extension of RET to additional training contexts result in further increases in production of CIUs and increased length and complexity of utterances
Will the effects of RET vary among participants with fluent aphasia participants with nonfluent aphasia who present with mild to moderate verbal production deficits and participants with nonfluent aphasia who present with severe verbal production deficits
Effects effects on production of CIUs and on measures of functional communication
Will changes in measures of functional communication be observed following administration of RET
A series of single-subject experimental designs across subjects behaviors and contexts will be conducted to address these questions Twenty-four adults with chronic moderate to severe aphasia secondary to unilateral left-hemisphere brain-injury will serve as participants for this investigation
Extended description of the protocol including information not already contained in other fields such as comparisons studied
Example
Sudden out-of-hospital cardiac arrest OOH-CA remains a significant cause of death in spite of recent declines in overall mortality from cardiovascular disease Existing methods of emergency resuscitation are inadequate due to time delays inherent in the transport of a trained responder with defibrillation capabilities to the side of the OOH-CA victim Existing Emergency Medical Services EMS systems typically combine paramedic Emergency Medical Technician EMT services with some level of community involvement such as bystander cardiopulmonary resuscitation CPR training Some communities include automated external defibrillators AEDs at isolated sites or in mobile police or fire vehicles A comprehensive integrated community approach to treatment with AEDs would have community units served by these volunteer non-medical responders who can quickly identify and treat a patient with OOH-CA Such an approach is termed Public Access Defibrillation PAD
Comparisons Community units trained and equipped to provide public access defibrillation in addition to optimal standard care compared to community units trained to provide optimal standard care recognition of out-of-hospital cardiac arrest 911 access and cardiopulmonary resuscitation
The purpose of the proposed research is to thoroughly evaluate the effects of Response Elaboration Training RET with persons with aphasia Specifically the proposed research investigation is designed to delineate the outcomes that may be expected with RET The study is also designed to improve outcomes in the area of stimulus generalization effects of treatment by testing a modification of RET designed to facilitate generalization The specific experimental questions to be addressed are as follows
Will RET result in increased production of correct information units and increased length and changes in composition of utterances as measured in trained and untrained picture descriptions story retells conversations with significant othersfamily membersfriends and personal recounts
Will modification and extension of RET to additional training contexts result in further increases in production of CIUs and increased length and complexity of utterances
Will the effects of RET vary among participants with fluent aphasia participants with nonfluent aphasia who present with mild to moderate verbal production deficits and participants with nonfluent aphasia who present with severe verbal production deficits
Effects effects on production of CIUs and on measures of functional communication
Will changes in measures of functional communication be observed following administration of RET
A series of single-subject experimental designs across subjects behaviors and contexts will be conducted to address these questions Twenty-four adults with chronic moderate to severe aphasia secondary to unilateral left-hemisphere brain-injury will serve as participants for this investigation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None