Ignite Creation Date:
2024-05-06 @ 1:05 AM
Last Modification Date:
2024-10-26 @ 10:59 AM
Study NCT ID:
NCT01726725
Status:
UNKNOWN
Last Update Posted:
2012-11-16
First Post:
2012-11-07
Brief Title:
Hemifacial Spasm and Desflurane
Sponsor:
University of Manitoba
Organization:
University of Manitoba
Study Overview
Official Title:
Investigating the Etiology of Hemifacial Spasm HFS The Role of Desflurane
Status:
UNKNOWN
Status Verified Date:
2012-11
Last Known Status:
ENROLLING_BY_INVITATION
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
HFS
Brief Summary:
Patients are chosen to participate in this study because they will undergo a particular type of brain surgery to treat their hemifacial spasm This surgery is called microvascular decompression MVD and involves the facial nerve The facial nerve is being compressed by one or more blood vessels and this contact produces the facial twitches The investigators do not know why a blood vessel that touches the facial nerve produces facial twitches The investigators are interested in investigating this during your surgery A total of 25 participants are expected to participate in this study
Detailed Description:
Intra Operative Monitoring IOM is a standard and routine medical practice for patients having MVD surgery IOM is done to make sure that the hearing and face nerves are not accidentally bumped or damaged during surgery After anesthetic induction the neurophysiologist places electrodes for the nerves on the scalp and muscles Stimulation and monitoring of muscle twitches are all common safe and painless medical procedures
In this study the investigators would like to measure the nerve and muscle function on the normal side and compare it to nerve and muscle function on the abnormal side during different levels of the anesthetic desflurane In order to monitor the normal side of the face one additional set of electrodes will be placed in the facial muscles The investigators will compare responses to three different levels of anesthetic The technique used will be motor evoked potentials The effect of the anesthesia on the lateral spread response will also be examined This response is evident only on the symptomatic side These observations will take approximately 10 to 15 minutes and will not delay or lengthen the surgery
In this study the investigators would like to measure the nerve and muscle function on the normal side and compare it to nerve and muscle function on the abnormal side during different levels of the anesthetic desflurane In order to monitor the normal side of the face one additional set of electrodes will be placed in the facial muscles The investigators will compare responses to three different levels of anesthetic The technique used will be motor evoked potentials The effect of the anesthesia on the lateral spread response will also be examined This response is evident only on the symptomatic side These observations will take approximately 10 to 15 minutes and will not delay or lengthen the surgery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None