Ignite Creation Date:
2024-05-06 @ 1:03 AM
Last Modification Date:
2024-10-26 @ 10:58 AM
Study NCT ID:
NCT01719211
Status:
RECRUITING
Last Update Posted:
2023-11-08
First Post:
2012-10-30
Brief Title:
Genetic Basis of Mitral Valve Prolapse
Sponsor:
Massachusetts General Hospital
Organization:
Massachusetts General Hospital
Study Overview
Official Title:
Genetic Basis of Mitral Valve Prolapse
Status:
RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MVP
Brief Summary:
The investigators have successfully identified two novel genetic loci for MVP on chromosomes 11 and 13 and are searching for altered genes in these regions This requires recruiting large families who may have MVP linked to these or other chromosomes and obtaining DNA samples from 1000-1500 individually affected patients to study the relation between DNA markers throughout the genome and MVP It is our expectation that the results of this study will lead to the discovery of genes responsible for MVP This will lead to improved understanding of the disease and in turn improved ability to treat and prevent progression in genetically susceptible individuals
Detailed Description:
This is a genome-wide association study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None