Ignite Creation Date:
2024-05-05 @ 11:44 AM
Last Modification Date:
2024-10-26 @ 9:12 AM
Study NCT ID:
NCT00115713
Status:
COMPLETED
Last Update Posted:
2007-03-23
First Post:
2005-06-23
Brief Title:
Effects of Aerobic Exercise Versus Weight Training in Breast Cancer Survivors During Chemotherapy
Sponsor:
University of Alberta Physical Education
Organization:
University of Alberta Physical Education
Study Overview
Official Title:
Comparison of Aerobic Versus Resistance Exercise Training in Enhancing Quality of Life in Early Stage Breast Cancer Survivors Receiving Chemotherapy A Multi-Centre Randomized Trial
Status:
COMPLETED
Status Verified Date:
2007-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to compare the effects of two different types of exercise aerobic exercise training AET and resistance exercise training RET on quality of life QoL in early stage breast cancer survivors receiving chemotherapy It is hypothesized that both AET and RET would have beneficial effects on QoL
Detailed Description:
The study was a prospective three-armed randomized controlled trial Participants were stratified by site Edmonton Ottawa and Vancouver and planned chemotherapy protocol taxane-based versus nontaxane-based and randomly assigned to AET RET or usual care UC in a 111 ratio using a random-numbers table Participants assigned to the AET group were asked to perform aerobic exercise three times per week on a recumbent or upright cycle ergometer treadmill or elliptical Exercise duration began at 15 minutes for weeks 0 through 2 and then systematically increased by 5 minutes every three weeks thereafter to 45 minutes for weeks 18 and beyond Exercise intensity began at 60 of VO2max for weeks 0 through 2 and then systematically increased by 10 every 6 weeks thereafter to 80 of VO2max for weeks 12 and beyond Warm-up and cool-down periods consisted of 5 minutes of aerobic activity at the power output of the ventilatory equivalent for oxygen approximately 50 of peak oxygen consumption Participants assigned to the RET group were asked to perform resistance exercise three times per week which consisted of two sets of 10 repetitions of 9 different exercises performed at 60-70 of 1-repetition maximum The specific exercises were leg extension leg curl calf raises chest press latissimus pulldown overhead press triceps extension biceps curls and modified curl-ups Resistance was increased by approximately 10 or the next weight level when the participant was able to complete 12 repetitions per set without difficulty
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None