Ignite Creation Date:
2025-12-25 @ 3:53 AM
Ignite Modification Date:
2025-12-26 @ 2:42 AM
Study NCT ID:
NCT04050202
Status:
COMPLETED
Last Update Posted:
2024-07-22
First Post:
2019-08-07
Is NOT Gene Therapy:
False
Has Adverse Events:
True
Brief Title:
Attachment and Biobehavioral Catch-up for Depression
Sponsor:
University of California, San Francisco
Organization:
Study Overview
Official Title:
Attachment and Biobehavioral Catch-up for Depression Intervention
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ABC
Brief Summary:
The overarching goal is to pilot the Attachment and Biobehavioral Catch-up (ABC) intervention for mothers with heightened depressive symptom and their children with heightened internalizing symptoms.
Detailed Description:
Exposure to maternal depressive symptoms increases children's risk for developing anxiety and depressive symptoms ("internalizing symptoms"). Maternal depressive symptoms and children's internalizing symptoms may be reciprocally related over time. Optimal interventions for children's internalizing symptoms may involve treatment components for mothers, children, and the maternal-child relationship. The Attachment and Biobehavioral Catch-up (ABC) intervention is a empirically-supported, family-based treatment program that has been shown to be beneficial for children in varied high-risk family environments, but has yet to be tested among mothers and children recruited on the basis of heightened depressive and internalizing symptoms, respectively. The overarching goal is to examine the acceptability, feasibility, and preliminary effects of the ABC program on a sample of mother-child dyads (n = 20) with heightened depressive and internalizing symptoms. Our specific aims are:
1. To evaluate the feasibility and acceptability of ABC for mothers with depressive symptoms and their offspring with internalizing symptoms
2. To explore whether children who receive ABC show improvement in internalizing symptoms from pre- to post-intervention
3. To explore whether mothers who receive ABC show improvement in depressive symptoms from pre- to post-intervention
4. To explore whether parents and children who receive ABC show more adaptive physiological responses to stress from pre- to post-intervention
1. To evaluate the feasibility and acceptability of ABC for mothers with depressive symptoms and their offspring with internalizing symptoms
2. To explore whether children who receive ABC show improvement in internalizing symptoms from pre- to post-intervention
3. To explore whether mothers who receive ABC show improvement in depressive symptoms from pre- to post-intervention
4. To explore whether parents and children who receive ABC show more adaptive physiological responses to stress from pre- to post-intervention
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| K23MH113709 | NIH | None | https://reporter.nih.gov/quic… | View |