Ignite Creation Date:
2024-05-06 @ 12:52 AM
Last Modification Date:
2024-10-26 @ 10:55 AM
Study NCT ID:
NCT01670903
Status:
UNKNOWN
Last Update Posted:
2012-08-22
First Post:
2012-08-19
Brief Title:
The Effect of Angiotensin II Type 1 Receptor Antagonists on the Size and Expansion Rate of Abdominal Aortas in Hypertensive Patients
Sponsor:
Sheba Medical Center
Organization:
Sheba Medical Center
Study Overview
Official Title:
the Effect of Angiotensin II Type 1 Receptor Antagonists on the Size and Expansion Rate of Abdominal Aortas in Hypertensive Patients
Status:
UNKNOWN
Status Verified Date:
2012-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Abdominal aortic aneurysm AAA is a common disease that develops from degeneration of the aortic wall The natural history of AAA is gradual expansion and if left untreated may result in rupture and death The mechanism of the development of this disease is unknown however it appears to be multifactorial and possibly related to degradation processes within the arterial wall There is growing evidence that Angiotensin receptor blockers ARBS may have an inhibitory effect on remodelling processes within the arterial wall thus inhibiting degeneration of the vessel wall
Study hypothesis ARBS are associated with smaller diameters of aortas among hypertensive patients and are associated with a lower rate of aortic expansion compared to other antihypertensive drugs
Study hypothesis ARBS are associated with smaller diameters of aortas among hypertensive patients and are associated with a lower rate of aortic expansion compared to other antihypertensive drugs
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None