Ignite Creation Date:
2024-05-06 @ 12:52 AM
Last Modification Date:
2024-10-26 @ 10:55 AM
Study NCT ID:
NCT01672723
Status:
COMPLETED
Last Update Posted:
2016-01-14
First Post:
2012-08-20
Brief Title:
Neuropharmacological Basis of Social Connection The Role of Opioids
Sponsor:
University of California Los Angeles
Organization:
University of California Los Angeles
Study Overview
Official Title:
Neuropharmacological Basis of Social Connection The Role of Opioids
Status:
COMPLETED
Status Verified Date:
2015-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
From birth we rely on others for comfort and care and derive pleasure from being together Research from the fields of health psychology social psychology and public health converge to highlight the importance of having and maintaining good relationships for overall health Indeed having close friends and family and feeling connected to them has been called a basic need similar to our need for food and water It may not be a coincidence then that feelings of connection rely on similar systems in the body as other needs that are both basic and highly pleasing and rewarding For instance its possible that opioids a substance in the body associated with pleasant euphoric feelings may also be important for connecting with others This study will examine the role of opioids in feeling connected to others by administering a drug called naltrexone that effects opioid processing in the body on perceptions and feelings toward a number of tasks in the lab Additionally to assess the effects of naltrexone outside of the lab participants will complete daily diary responses via text and online surveys
40 participants will take both placebo and naltrexone Participants will complete two sessions one in each drug condition in which they complete a number of tasks including reading messages on a computer screen holding a number of objects and viewing images while undergoing electric shocks Participants will also complete a daily diary for 14 days while on naltrexone and placebo Prior to these lab sessions participants will be screened at UCLAs Clinical Translational Research Center CTRC to ensure that they are healthy and that it is safe for them to take the study drug
We hypothesize that people will report feeling less socially connected when on naltrexone compared to placebo and will show subsequent changes in social behavior outside of the lab
40 participants will take both placebo and naltrexone Participants will complete two sessions one in each drug condition in which they complete a number of tasks including reading messages on a computer screen holding a number of objects and viewing images while undergoing electric shocks Participants will also complete a daily diary for 14 days while on naltrexone and placebo Prior to these lab sessions participants will be screened at UCLAs Clinical Translational Research Center CTRC to ensure that they are healthy and that it is safe for them to take the study drug
We hypothesize that people will report feeling less socially connected when on naltrexone compared to placebo and will show subsequent changes in social behavior outside of the lab
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None