Ignite Creation Date:
2024-05-06 @ 12:48 AM
Last Modification Date:
2024-10-26 @ 10:55 AM
Study NCT ID:
NCT01665573
Status:
COMPLETED
Last Update Posted:
2022-03-11
First Post:
2012-07-11
Brief Title:
Cannabinoid Augmentation of Fear Response in Humans
Sponsor:
Yale University
Organization:
Yale University
Study Overview
Official Title:
Cannabinoid Augmentation of Fear Response in Humans
Status:
COMPLETED
Status Verified Date:
2022-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this double blind randomized controlled proof-of-concept study is to test the effects of cannabinoid receptor augmentation on the facilitation of fear conditioning On three days over not more than two weeks subjects will be trained to associate cues with two different stimuli then this association will be extinguished Cannabinoid receptor stimulation will be accomplished indirectly by harnessing the brains capacity to endocannabinoids through the administration of an enzyme FAAH inhibitor that prevents degradation of anandamide Subjects will receive placebo or the FAAH-inhibitor PF-04457845 Some details of this study have not been disclosed to preserve the study design
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None