Ignite Creation Date:
2024-05-05 @ 11:42 AM
Last Modification Date:
2024-10-26 @ 9:12 AM
Study NCT ID:
NCT00111267
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
2005-05-18
Brief Title:
Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People
Sponsor:
Wageningen University
Organization:
Wageningen University
Study Overview
Official Title:
The Effect of Oral Vitamin B12 Supplementation on Cognitive Performance in Elderly People the Brain12 Study
Status:
COMPLETED
Status Verified Date:
2005-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this trial is to study the effects of oral vitamin B12 supplementation and vitamin B12 combined with folic acid supplementation on cognitive performance for 24 weeks in elderly people with mild vitamin B12 deficiency
Detailed Description:
Mild vitamin B12 deficiency is highly prevalent in old age Reasons for this high prevalence are not fully understood but include atrophic gastritis and bacterial overgrowth which affect the absorption active of food-bound vitamin B12 In contrast the ability to absorb crystalline vitamin B12 eg the form found in fortified foods or vitamin pills remains intact in old age In both healthy and cognitively impaired elderly people associations between vitamin B12 status and cognitive performance have been observed and the follow-up of geriatric patients suggests effects of parenteral treatment in early cognitive impairment
We investigated whether daily oral supplementation with 1000 μg vitamin B12 or 1000 μg vitamin B12 combined with 400 μg folate for 24 weeks improves cognitive performance in people over 70 years with vitamin B12 deficiency
We investigated whether daily oral supplementation with 1000 μg vitamin B12 or 1000 μg vitamin B12 combined with 400 μg folate for 24 weeks improves cognitive performance in people over 70 years with vitamin B12 deficiency
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| ZonMW 21000067 | None | None | None |