Ignite Creation Date:
2025-12-25 @ 3:28 AM
Ignite Modification Date:
2026-02-21 @ 5:53 AM
Study NCT ID:
NCT02430805
Status:
COMPLETED
Last Update Posted:
2015-04-30
First Post:
2010-02-05
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Predisposition and Transition Mechanisms From Arterial Hypertension to Heart Failure
Sponsor:
Central Hospital, Nancy, France
Organization:
Study Overview
Official Title:
Genetics and Genomics of Hypertension Associated With Microinflammation, Oxydative Stress, Chronic Renal Disease and Heart Failure (A2-B2-B3)
Status:
COMPLETED
Status Verified Date:
2010-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Hypercare
Brief Summary:
This project aims at investigating the genetic, genomic and proteomic basis of hypertension and susceptibility to hypertension-related end organ damage (renal damage and heart failure). It will include cross sectional as well as follow-up studies with a large number of subjects and variety of phenotypes, to explore the pathophysiology of hypertension and hypertension-related disease.
Detailed Description:
In all index patients and recruited family members, recorded data will include the following :
* Past medical history, drug history and family history
* Physical examination
* Height, weight, waist and hip circumference
* Cardiac examination
* Vascular examination
* Blood pressure
* Plasma and urine samples
* Body composition (DEXA)
* Tissue Doppler imaging
* Past medical history, drug history and family history
* Physical examination
* Height, weight, waist and hip circumference
* Cardiac examination
* Vascular examination
* Blood pressure
* Plasma and urine samples
* Body composition (DEXA)
* Tissue Doppler imaging
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: