Viewing Study NCT01610518



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Study NCT ID: NCT01610518
Status: COMPLETED
Last Update Posted: 2012-06-04
First Post: 2012-05-31

Brief Title: The Glycemic Response Elicited by Beta-glucans of Different Physical Properties and Form
Sponsor: Guelph Food Research Centre
Organization: Guelph Food Research Centre

Study Overview

Official Title: The Glycemic Response Elicited by Beta-glucans of Different Physical Properties and Form
Status: COMPLETED
Status Verified Date: 2012-06
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The ability of oat β-glucan to lower postprandial glycemic responses has been attributed to the viscosity of the solution in which the fibre is solubilized To our knowledge no studies have investigated the effect of β-glucan solutions on glycemic response when concentration and thus viscosity is varied by changing the solution volume but not the β-glucan dose Therefore the investigators will test the effects of altering β-glucan solution viscosity by altering solution volume at a fixed amount of β-glucan fibre
Detailed Description: The ability of β-glucan to lower postprandial glycemic responses has been attributed to the viscosity of the solution in which the fibre is solubilized It has been demonstrated that the viscosity of a β-glucan solution increases with the molecular weight MW of β-glucan polymers as well as the dose or concentration C of those polymers in solution Numerous studies have shown that glycemic response-lowering is strengthened when the C of a β-glucan solution of fixed liquid volume is increased by increasing β-glucan dose However the C of a β-glucan solution depends on not only the amount of fibre present but also on the solution volume To our knowledge no studies have investigated the effect of β-glucan solutions on glycemic response when C and thus viscosity is varied by changing the solution volume but not the β-glucan dose Therefore the investigators will test the effects of altering β-glucan solution viscosity by altering solution volume at a fixed amount of β-glucan fibre Knowing how to incorporate β-glucan into solution so that its physiological benefits are preserved will assist in the development of β-glucan-containing functional foods

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None