Ignite Creation Date:
2025-12-25 @ 3:21 AM
Ignite Modification Date:
2025-12-31 @ 11:01 PM
Study NCT ID:
NCT05007405
Status:
COMPLETED
Last Update Posted:
2024-09-19
First Post:
2021-08-11
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Spectrum of Bacterial Infections in Rheumatology
Sponsor:
Hôpital NOVO
Organization:
Study Overview
Official Title:
Spectrum of Bacterial Infections in Rheumatology and the Role of Urinary Tract Infection
Status:
COMPLETED
Status Verified Date:
2021-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SIBERIE
Brief Summary:
Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are :
* To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome
* To compare OAI of urinary origin with those with another origin
* To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome
* To compare OAI of urinary origin with those with another origin
Detailed Description:
This retrospective study will be conducted on medical files. Patients will be mainly selected on :
* A proved osteoarticular infection (OAI) diagnosed in the department of rheumatology of the René Dubos hospital from 1° January 2010 to 31 December 2020.
* Adult patients 18 year's old or older
* Infection proved by positive culture in the osteoarticular site and/or blood (with typical clinical and imaging features)
The followed OAI are not included :
* Infection on prosthetic joint, materiel ; post-operative OAI ; osteomyelitis
* Brucellosis ; Lyme disease
Patients are selected from the codification of the hospitalization ; medical files are reviewed by the investigators.
OAI of urinary origin is defined either by the same micro-organism in urine and osteo-articular sample (or blood) or a bacteria in the osteo-articular sample in conjunction with : urologic pathology, recurrent urinary tract infection, urologic surgery, antibiotic therapy.
* Characteristics of three populations will be compared :
* \- OAI of urinary origin
* \- OAI of another origin (skin, etc)
* \- OAI without known origin Characteristics include : gender, age, risk factors, site of osteo-articular infection, type of micro-organism, type of positive sample(s), blood cultures, urinary cultures, duration of symptoms, site of primary infection and/or type of contamination, biological results, echocardiography, imaging results, type of treatment (medical, surgical), outcome, duration of hospitalization, intensive unit care stay, death at hospital.
* A proved osteoarticular infection (OAI) diagnosed in the department of rheumatology of the René Dubos hospital from 1° January 2010 to 31 December 2020.
* Adult patients 18 year's old or older
* Infection proved by positive culture in the osteoarticular site and/or blood (with typical clinical and imaging features)
The followed OAI are not included :
* Infection on prosthetic joint, materiel ; post-operative OAI ; osteomyelitis
* Brucellosis ; Lyme disease
Patients are selected from the codification of the hospitalization ; medical files are reviewed by the investigators.
OAI of urinary origin is defined either by the same micro-organism in urine and osteo-articular sample (or blood) or a bacteria in the osteo-articular sample in conjunction with : urologic pathology, recurrent urinary tract infection, urologic surgery, antibiotic therapy.
* Characteristics of three populations will be compared :
* \- OAI of urinary origin
* \- OAI of another origin (skin, etc)
* \- OAI without known origin Characteristics include : gender, age, risk factors, site of osteo-articular infection, type of micro-organism, type of positive sample(s), blood cultures, urinary cultures, duration of symptoms, site of primary infection and/or type of contamination, biological results, echocardiography, imaging results, type of treatment (medical, surgical), outcome, duration of hospitalization, intensive unit care stay, death at hospital.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?: